放疗联合肝动脉化疗栓塞治疗原发性肝癌的临床效果分析

Clinical Effects of Radiotherapy Combined with Hepatic Artery Chemo-embolization on the Treatment of Primary Hepatic Carcinoma

目的:探讨放疗联合肝动脉化疗栓塞治疗原发性肝癌的临床效果。方法:选取2009年2月至2011年2月入住我院的60例已确诊且不能进行手术切除的Ⅲ、Ⅳ期原发性肝癌患者,采用三维适形放疗(3D-CRT)联合肝动脉化疗栓塞(TACE)治疗。结果:近期疗效有效率为76.67%。0.5、1、2年的生存率分别为87.4%、65.2%、38.7%。平均生存时间为25.6个月。结论:将放疗联合肝动脉化疗栓塞应用到原发性肝癌的治疗中,能够有效地控制患者病情,提高患者生活质量,延长患者生存期,对于不能进行手术治疗的中晚期患者具重要的实践与运用价值,值得推广。

Objective： To investigate the clinical effect and safety of radiotherapy combined with hepatic artery chemo-embolization on the treatment of hepatic carcinoma.Methods： 60 patients who were diagnosed with primary hepatic carcinoma at stage III and IV but could not operate from February 2009 to February 2011 were selected.Then they were conducted three-dimensional conformal radiotherapy（3D-CRT） combined with transcatheter arterial chemo-embolization（TACE）.Results： The short-term efficacy rate was 76.67%.The rate of survival at half a year,one year and two years was 87.4%,65.2% and 38.7%,the average survival time was 25.6 months.Conclusion： 3D-CRT combined with TACE could effectively control the disease,improve the quality of patients＇ life,prolong the survival time of patients.It has important practical value for clinical application,and it is worth to promote.