摘要
目的:研究β-环糊精(β-CD)对苦味中药的掩味规律。方法:选取黄柏、龙胆、穿心莲等6种代表性苦味中药饮片的水煎液和小檗碱水溶液为研究载体,以不同质量分数的β-CD为掩味剂,考察加入掩味剂前、后溶液的苦度变化。结果:β-CD对多种苦味中药有较好的掩味效果,除龙胆外,β-CD的掩味效果优于磺丁基醚-β-CD。结论:β-CD可用于多种苦味中药饮片水煎液的掩味。
Objective： To study the mechanism of bitter taste masking by β-cyclodextrin（β-CD） for traditional Chinese medicine（TCM）.Method： With decoction of Phellodendri Chinensis Cortex,Gentianae Radix et Rhizma,Andrographis Herba,et al.and water solution of berberine as model drugs,sulfobutyl ether-βCD（SBE-β-CD） and β-CD as taste masking agent,the degree of bitter before and after masking was evaluated by mouth-tasting.Result： β-CD showed more significant effects of bitter taste masking than SBE-β-CD,except Gentianae Radix et Rhizma.Conclusion： This study proved that β-CD could used as taste-masking agent for decoction of several TCM.
出处
《中国实验方剂学杂志》
CAS
北大核心
2013年第12期1-4,共4页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家自然科学基金青年基金项目(81001646)
