摘要
腹膜透析(PD)是终末期肾脏疾病治疗的有效方法之一,可替代肾脏的部分功能。由于PD不能代替肾脏的全部功能,体内仍然存在许多影响患者长期生存的因素。长期接受PD的患者体内普遍存在慢性炎症状态,其原因是复杂的、多种因素共同参与的,主要包括透析相关性及非透析相关性因素。体内炎性因子的增高对腹膜结构与功能、心血管系统、营养状况、残肾功能、透析充分性以及生存质量都有不利影响。如何减轻炎症状态,提高PD患者生存率是目前研究的热点。
Peritoneal dialysis is one of the effective treatment of end-stage renal disease, which can sub-stitute parts of renal function. Because not all of the functions of the kidney can be substituted by peritoneal dialysis, many factors in vivo still affect the patients for long-term survival. Chronic inflammation is highly prevalent in long-term peritoneal dialysis population. The causes of inflammation are usually complex and muhifactorial, involving both dialysis-related and dialysis-unrelated factors. The elevated inflammatory factors have negative influence on the peritoneal structure and function, cardiovascular system, nutritional status, residual renal function, dialysis sufficiency and quality of life. How to reduce inflammatory state and improve the peritoneal dialysis patients＇ survival rate are the research hotspots.
出处
《医学综述》
2013年第12期2142-2144,共3页
Medical Recapitulate
关键词
腹膜透析
炎症状态
炎性因子
Peritoneal dialysis
Inflammatory state
Inflammatory factors
