维持性血液透析患者炎症及营养状况分析

Analysis on Chronic Inflammation and Nutrition Status in Maintenance Hemodialysis Patients

目的比较维持性血液透析(MHD)患者加强质量管理前后慢性炎症、营养不良状况。方法选取2011年1月在煤炭总医院血液净化中心就诊、有完整资料并透析治疗1年以上的MHD患者42例,比较在2011年1～3月和年末10～12月的C反应蛋白(CRP)、血清白蛋白(ALB)、血红蛋白(Hb)水平及Kt/V值,同时按性别分组比较上述指标。结果年末Kt/V、ALB及Hb值较年初有所改善(P<0.05),但CRP无统计学意义(P>0.05)。按性别分组,男女CRP、ALB水平无显著差异(P>0.05),但女性患者Kt/V值显著优于男性患者(P<0.05)。结论 MHD患者普遍存在慢性炎症,常规透析不能改善其病理状态。通过综合处理,患者营养不良状况可得到改善。

Objective To compare the status of chronic inflammation and nutrition before and afler enhancing control of treatment in maintenance hemodialysis patients. Methods There were 42 MHD patients treated by hemodialysis for over one year in China Meitan General Hospital in Jan. 2011 recruited in this study. We reviewed and compared the data of C-reactive protein （CRP） , serum albumin （ALB） , hemoglobin （Hb） and Kt/V in the beginning （ January-March ） and the end （Octorber-December） of the year of 2011, and we compared the same items between the male and female groups. Results The clinical data of ALB, HB and Kt/V in the end of 2011 were better than that in the beginning of the 2011 （ P 〈 0.05 ）. But no difference was found on the item of CRP in the two groups（ P 〉 0. 05 ）. On the items of CRP and ALB, there were no remarka- ble differences between male and female groups（ P 〉 0.05 ）, but Kt/V of the female was better than the male （P 〈 0.05 ）. Conclusion Prevalence of chronic inflammation in MHD patients is high, and routine dialysis treatment cannot change the status. Malnutrition condition can be imnroved bv comnrehensive treatment.