盐酸克林霉素和克林霉素磷酸酯致肾损害的比较

Comparison of renal impairment induced by clindamycin hydrochloride and clindamycin phosphate

克林霉素是临床常用的抗菌药物,近年来其肾损害的不良反应备受关注。通过对国内文献报道的分析表明,与克林霉素磷酸酯比较,盐酸克林霉素引起肾毒性的时间早、程度严重,是需要临床密切关注和进一步研究的风险信号。

Clindamycin is an antimicrobial drugs commonly used in clinical. The adverse reactions of renal impairment is concerned in recent years. By analyzing the literature, to provide the signal that the renal toxicity of clindamycin hydrochloride is more earlier and serious than clindamycin phosphate.