摘要
目的:进行补阳还五汤配方简化研究,并比较原方与新方对小鼠肠壁微动脉循环作用差别。方法:以黄芪甲苷含量和出膏率为指标,采用均匀设计法进行补阳还五汤组成简化,再检测两种复方对滴加去甲肾上腺素后小鼠肠壁微动脉循环的影响。结果:新方最佳剂量配伍比例为:当归11 g,川芎11 g,赤芍8.8 g,红花11 g;原方和新方药物能不同程度扩张滴加去甲肾上腺素后小鼠肠壁微动脉。结论:补阳还五汤新方及原方对滴加去甲肾上腺素小鼠肠壁微动脉毛细血管的扩张作用程度基本一致。
Objective ： To investigate the drug combination of Buyang Huanwu compatibility and observe the effects of different combinations on microcirculation of mesentery styrtoles. Methods ： Uniform design was used to study the combination, obseviong the effects of extraction to the miceg mesentery microcirculation. Results：The best dose ratio of the combination was Chinese angeli- cal 1 g, Chuanxiongl 1 g, Chishao 8.8 g, Honghual 1 g. Both extractions had same degrees at expensing role of capillary arteriole. Conclusion：Extract of Buyang Huanwu Decoction can improve the mieroeirculation of mesentery in mice.
出处
《辽宁中医杂志》
CAS
2013年第6期1115-1116,共2页
Liaoning Journal of Traditional Chinese Medicine
关键词
补阳还五汤
均匀设计
黄芪甲苷
微循环
Buyang Huanwu Decoction
uniform design
Astragaloside
microcirculation
