生大黄辅助治疗重症急性胰腺炎临床疗效研究

The Clinical Adjuvant Treatment Efficacy Study of Rhubarb on Severe Acute Pancreatitis

目的:探讨生大黄辅助治疗重症急性胰腺炎的临床治疗效果。方法:重症急性胰腺炎患者90例,随机分成两组,对照组45例患者采取常规治疗方案,观察组45例患者在常规治疗方案的基础上给予生大黄浸泡液胃管内注入及灌肠治疗。观察两组患者疗效、症状改善情况及患者腹腔内压改善情况。结果:早期有效率比较,观察组(80.0%)高于对照组(66.7%),差异有统计学意义(P<0.05),观察组降低了患者中转手术率和死亡率,在改善临床症状、腹腔内压、炎症反应、氧化损伤方面见效果显著。结论:生大黄辅助治疗重症急性胰腺炎,有利于临床症状的改善,早期降低患者腹腔内压,提高患者的整体治疗效果。

Objective：To explore the rhubarb-assisted clinical effects on severe acute pancreatitis patients. Methods：90 cases of patients with severe acute pancreatitis were divided into two groups, each group of 45 cases. Control group was given the conventional treatment, the observation group was given rhubarb soaking liquid gastric tube injection therapy on the bases of conventional treatment options. Results ： Early efficiency comparison showed that observation group which had 80.0% was higher than that in the control group which had 66.7%, the difference was statistically significant （ P 〈 0. 05 ）. The observation group reduced the rates of surgical intervention and death, had a significant effect in improving clinical symptoms and intra - abdominal pressure. Conclusion：The rhubarb adjuvant treatment of severe acute pancreatitis is conducive to the improvement of clinical symptoms, early to reduce the intra- abdominal pressure,improve the patient＇s overall treatment effect.