生脉注射液辅助治疗慢性阻塞性肺疾病150例

Clinical Efficacy of Shengmai Injection for 150 Cases of Patients with Chronic Obstructive Pulmonary Disease

目的:探讨生脉注射液辅助治疗慢性阻塞性肺疾病的功能性改善以及临床疗效。方法:选取2010年10月———2012年10月期间就诊于本院的慢性阻塞性肺疾病患者150例进行回顾性分析并随机分为两组,每组75例。其中,对照组采用常规的方法进行治疗(如抗炎、平喘、止咳化痰、解痉氧疗等),而观察组则在对照组的基础上给予生脉注射液进行辅助治疗。记录两组患者各临床症状的消失时间以及住院时间,观察其治疗前后肺功能指标的改善情况以及两组免疫球蛋白的变化情况,比较临床疗效。结果:治疗后,观察组各临床症状的消失时间以及住院时间均短于对照组,其肺功能指标以及免疫球蛋白均显著改善;另外,观察组总有效率为97.33%,而对照组总有效率则为86.67%,可见观察组的的临床疗效明显高于对照组,经分析,各差异均具有统计学意义(P<0.05)。结论:生脉注射液辅助治疗慢性阻塞性肺疾病的疗效确切,安全性高,不但可以改善肺功能,还可提高患者机体免疫力,值得在临床上推广应用。

Objective：To explore the functional improvement and efficacy of Shengmai Injection for patients with chronic obstructive pulmonary disease. Methods ： 150 chronic obstructive pulmonary disease patients in our hospital from October 2010 to October 2012 were retrospectively analyzed. And they were randomly divided into two groups and 75 cases were in each group. The control group was treated with conventional treatment such as anti - inflammatory, anti-asthma, cough and phlegm and antispasmodic oxygen therapy. The observation group was treated with Shengmai Injection on the basis of the treatment in control group. The symptoms＇ disappearing time and hospital time of the two groups were recorded. The improvement of lung function index and the changes of the immunoglobulin were observed before and after treatment. The clinical efficacy was compared. Results ： After treatment, some symptoms＇ disappearing time and hospital time of the observation group were shorter than those in the control group. Spirometry indicators as well as immune globulin were significantly improved. In addition, the total effective rate of the observation group was 97.33% ,while of the control group was 86.67%. The efficacy of the observation group was significantly higher than that of the control group and there was statistical significant difference （ P 〈 0. 05 ）. Conclusion ： Shengmai Injection can improve the lung function and patients＇ immunity. It is effective and safe and is worth to be used in clinical practice.