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反刍动物Ghrelin研究进展 被引量：4

Progress on Ghrelin in Ruminants
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摘要 Ghrelin是生长激素促泌素受体至今发现的唯一内源性配体,主要分泌于胃的脑肠肽,具有促进生长激素释放和调节食欲等广泛生物学作用。目前对于Ghrelin的研究主要集中在鼠类和人类,而关于反刍动物的研究相对较少,深度也不够。论文概述了Ghrelin及其受体的发现和反刍动物Ghrelin的组织分布;从Ghrelin对生长激素分泌的影响,促进食欲、调节能量平衡,调控生殖等方面阐述了Ghrelin对反刍动物的生物学作用,从摄食和内分泌等因素探讨了反刍动物Ghrelin分泌的调节,以期为进一步开展反刍动物Ghrelin及其受体的研究提供参考。 So far,ghrelin is the only endogenous ligand of growth hormone secretagogue receptors,mainly secreted from the stomach.Ghrelin was found with a wide range of biological effects： stimulation the release of growth hormone,regulation of appetite and so on.Studies on ghrelin were mostly focused on the rodent and human,and a few in ruminants.This article summarized the discovery of ghrelin and its receptors;the tissue distribution of ghrelin in ruminants;the biological functions of ghrelin,including the effect on growth hormone secretion,promoting appetite,regulating energy balance and reproduction;the regulation of ghrelin by feeding and endocrine in ruminants.
作者 刘璐 夏利宁 姚刚 赵红琼
机构地区 新疆农业大学动物医学学院
出处 《动物医学进展》 CSCD 北大核心 2013年第6期149-153,共5页 Progress In Veterinary Medicine
基金 新疆维吾尔自治区自然科学基金项目(2011211A025)
关键词 GHRELIN 反刍动物 内分泌 生长激素 食欲 Ghrelin ruminant endocrine growth hormone appetite
分类号 S852.2 [农业科学—基础兽医学]
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参考文献32

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二级参考文献25

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共引文献4

同被引文献157

  • 1姜冬梅,李士泽,康波,杨焕民,倪江,计红.冷应激蛋鸡呼吸频率、心电与血清酶活性的变化及其相互关系[J].中国兽医学报,2008,28(9):1077-1080. 被引量：8
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动物医学进展
2013年 第6期

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