塑料包装对药品质量和安全性能的影响及解决措施

Effect of Plastic Packaging on Medicine Quality and Safety Performance and Solutions

聚乙烯、聚氯乙烯、聚苯乙烯、聚丙烯等是药品包装常用塑料,其性能存在一些缺陷,影响着所包装药品的质量与安全性能。其影响因素主要有:塑料对药物的吸附作用,塑料添加剂向药物的迁移,聚合物单体的分解,材料的透气透湿性能等。可采取科学选择药品包装材料、大力推广使用医用环保增塑剂、推行医用塑料包装市场准入制度、严格控制药品流通环境安全等解决措施,以降低塑料包装对药品质量与安全性能造成的消极影响。

Abstract ： The plastic packaging materials for medicine commonly include polyethylene, polyvinyl chloride, polystyrene, polypropylene, etc. The performances of these materials have some defects that affect the medicine quality and safety performance. The main influencing factors are： plastic adsorption of drugs, plastics additive migration to the drug, the decomposition of polymer monomer, breathable moisture permeability of the material etc.. In order to reduce negative impacts on drug quality and safety performance due to plastic packaging, the solutions are put forward as choosing medicine packaging materials scientifically, promoting the use of medical environmental protection plasticizer vigorously, carrying out medical plastic packaging market access system, controlling the drug circulation environment security strictly etc..