延安市孕产妇弓形虫感染的血清学分析

Serologic analysis of toxoplasma infection among pregnant women in Yan′an

目的 :为了解延安市不良孕产史妇女及妇科病患者与正常妊娠结局者及健康妇女的 Toxo感染情况 .方法 :用 ELISA对 96 4份血清进行了 Toxo特异性 Ig M、Ig G抗体的检测 .结果 :( 1 )延安市正常妊娠结局产妇和健康妇女 Toxo总阳性率为1 1 .1 9% . ( 2 )各不良妊娠结局组的 Toxo总感染率分别为 1 8.75 %、41 .1 1 %和30 .0 0 % ,均明显高于正常结局组 1 0 .82 % ,其中死胎、习惯性流产及难免流产组有显著差异 ( P<0 .0 1 ) . ( 3)妇科病患者中 ,不孕症和盆腔炎组 Toxo总感染率分别为2 8.33%和 2 3.2 6 % ,均明显高于健康妇女组 1 2 .0 5 % ( P<0 .0 1 ,P<0 .0 5 ) .结果 :上述结果与国内多数学者报道相一致 ,从而进一步证实 ,Toxo感染可导致不良的妊娠结局 ,同时更加说明

Aim:To investigate into toxoplasma infection among normal and abnormal pregnant woman and diseased and healthy woman in Yan'an.Methods:964 sera samples are detected with ElISA to find out specific IgM and IgG antibodies.Results:(1)The total Toxoplasma infection rate among normal presnant woman and healthy woman in our city is 11 19%.(2)The Total infection rate among abnormal pregnant women are 18 75%,41 11%,and 30 00% respectionly, remarkesly higher than normal group(10 82%),and stillbirth, abortion and inevitable abortion have a significant difference ( P <0 05) (3)Among gynecology disease group, infertility gronp and pelvic inflammatory group have a infections rate of 28 33% and 23 26% respectively, both significantly higher than that of normal group of 12 05%( P <0 01, P <0 05).Conclusion:The results agree with most reports in China,demonstrating that toxo infection may lead to abnormal pregnesty, and illustrating that toxo infection may be one of the reasons for gynecology inflammatory diseases and infertility.