乙醇酸生产技术的研究进展

The Research Progress of Glycolic Acid Production Technology

首先概述现有的几种工业生产乙醇酸的方法,即氯乙酸水解法、羟基乙氰水解法、甲醛羰基化法、草酸电解法等,虽然能生产乙醇酸,但不符合安全环保理念;综合分析了当前改进乙醇酸生产技术路线的研究方向,如乙二醛氧化法、甲醛与甲酸或甲酸甲酯偶联法、草酸二甲酯加氢法、乙二醇选择性氧化法、微生物法;最后指出,乙醇酸工业生产的最佳发展方向,应当是以乙二醇为原料选择性氧化生产乙醇酸。

Several existing methods of industrial production of glycolic acid, chloroacetic acid hydrolysis, hydroxy acetonitrile hydrolysis, formaldehyde carbonylation, oxalic acid method, could produce glycolic acid but under safety and environmental requirements. The research direction of glycohc acid production technology was analyzed comprehensively, such as glyoxal oxidation, formaldehyde and formic acid or carboxyhc acid methyl ester coupling method, hydrogenation of dimethyl oxalate, glycol selective oxidation, and microbiological method. Finally, the best development direction of glycolic should be glycol selective oxidation.