摘要
1-甲基-2-氧代-3,6,7-三氧杂二环[2,2,2]辛烷是一种辛内酯类笼状化合物,具有乳脂味,可作为一种价格便宜的新型奶味香精用于食品中.采用丙酮酸和丙三醇为原料直接合成1-甲基-2-氧代-3,6,7-三氧杂二环[2,2,2]辛烷.以丙酮酸转化率为指标,研究了反应时间、催化剂用量、醇酸物质的量的比和反应温度对其合成的影响,通过液液萃取和重结晶获得其晶体,并采用核磁共振和红外光谱对目标产物进行表征.结果显示在反应时间4 h,催化剂用量为丙三醇和丙酮酸总质量的2.0%,醇酸物质的量的比为4∶1,反应温度为55℃时,丙酮酸转化率达到58%.
4-methyl-3-oxo-2,5,7-trioxabicyclo[ 2.2.2 ] octane is a novel cage compound with milk flavor, and can be used in foods as a cheap milk flavor. The compound was prepared from glycerin and pyruvic acid by liquid-liquid extraction and recrystallization, and the product was characterized by 133C NMR and infrared spectroscopy. In this paper, we studied the effects of reaction time, catalyst amount, molar ratio of glycerin to pyruvic acid and reaction temperature on the conversion rate of pyruvic acid. The results showed that the conversion rate of pyruvic acid reached 58% under the conditions of reaction time 4 hours, catalyst amount 2.0%, molar ratio of glycerin to pyruvic acid 4：1, and temperature 55 ℃.
出处
《河南工业大学学报（自然科学版）》
CAS
北大核心
2013年第3期66-69,共4页
Journal of Henan University of Technology：Natural Science Edition
基金
国家自然科学基金资助项目(31130042
31271885)
河南省科技攻关基金资助项目(072102270023)
广东省科技计划项目(2010B031700014
2010B050600003)
关键词
丙三醇
丙酮酸
合成
表征
glycerin
pyruvic acid
synthesis
characterization
