摘要
头孢地秦钠作为第三代头孢霉素广谱抗菌药物对β-内酰胺酶稳定,安全长效,抗菌谱广泛,且耐受性好,不良反应少,在临床上广泛应用。本文通过逆合成分析,对头孢地秦钠的制备方法进行了综述,并对头孢地秦钠的制备新方法及化学结构修饰进行了展望。
Cefodizime sodium was a third generation cephalosporin with a broad spectrum of antibacterial activity and was stable to β-1actamase, safe and effective, and widely used in clinical. Herein, the retrosyntbesis of cefodizime sodium was analysized and the preparation of cefodizime sodium was reviewed. Finally, the further prospects in synthesis of cefodizime sodium and structure modification were stated.
出处
《广东化工》
CAS
2013年第11期118-120,127,共4页
Guangdong Chemical Industry
基金
台州市科技计划项目(20111ky04)
关键词
头孢地秦钠
制备
综述
cefodizime sodium
preparation
review
