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酮咯酸氨丁三醇用于妇科术后患者自控镇痛50例的临床评价 被引量：6

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摘要 目的评价酮咯酸氨丁三醇联合吗啡用于妇科子宫切除术患者自控静脉镇痛的临床效应和不良反应。方法将100例子宫切除手术患者随机双盲分为酮咯酸氨丁三醇联合吗啡组(A组)和单纯吗啡组(B组)。手术结束前15 min开启自控静脉镇痛泵(PCIA),并于手术后不同时间点随访患者用药后呼吸和循环的变化,观察镇痛效果(VAS评分)并记录BCS舒适评分及D1/D2比值和可能出现的恶心、呕吐、尿潴留等副作用。结果两组镇痛效应无显著性差异(P>0.05),但B组恶心呕吐、尿潴留和皮肤瘙痒的发生率明显高于A组(P<0.05)。结论与单纯使用吗啡相比,酮咯酸氨丁三醇联合吗啡用于子宫切除术患者能明显降低吗啡恶心呕吐及瘙痒等副作用的发生率,并可增强吗啡的镇痛效果。
作者 王海
机构地区 浙江省嵊州市人民医院麻醉科
出处 《中国药业》 CAS 2013年第11期17-18,共2页 China Pharmaceuticals
关键词 酮咯酸氨丁三醇 吗啡 静脉自控镇痛 子宫切除术
分类号 R969.4 [医药卫生—药理学] R971.1 [医药卫生—药品]
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同被引文献60

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中国药业
2013年 第11期

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