摘要
目的:观察喙尾琵琶甲流浸膏对小鼠的镇痛及抗炎作用。方法:用热板法和醋酸扭体法测定小鼠的痛阈值,二甲苯耳肿胀法测定抗炎作用。结果:喙尾琵琶甲流浸膏高、低剂量组均能提高扭体小鼠痛阈值,高剂量组能显著提高热板实验小鼠痛阈值;喙尾琵琶甲抗炎作用不明显。结论:喙尾琵琶甲流浸膏具有明显的镇痛作用,抗炎作用不明显。
Objective： To investigate the analgesic and anti-inflammatory effect of the fluid extracts of Blaps rynchopetera Fairmaire （EBRF）. Methods： Hot-plate test and acetic acid twisting method were applied to determine the pain threshold of the mice, and mouse ear swelling test induced by dimethylbenzene was applied to evaluate the anti-inflammatory effect. Results： Both at high and low dose, fluid extracts of B. rynchopetera could prolong the mice pain threshold time in acetic acid twisting method, while only at the high dose could prolong the time in hot-plate test. There was no anti-inflammatory effect of B. rynchopetera. Conclusion： There is notable analgesic effect and no anti-inflammatory effect of B. rynchopetera.
基金
大理学院青年教师科研基金资助项目(KYQN2009-41)
关键词
喙尾琵琶甲流浸膏
热板实验
醋酸扭体实验
二甲苯致耳肿胀实验
fluid extracts of B. rynchopetera
hot-plate test
acetic acid twisting method
mouse ear swelling test induced by dimethylbenzene
