空腹血糖受损切点下调对糖调节受损患病率影响的调查

Investigation on Impact of Lowering Cut-Point of Impaired Fasting Glucose in Impaired Glucose Regulation

目的探讨下调空腹血糖受损切点后,本地区糖调节受损(IGR)患病情况分布的变化。方法选择2010年至2011年在我院进行健康体检者784例,按不同空腹血糖水平进行分组,分析患者IGR分布的变化情况。结果空腹血糖受损诊断标准下调后,空腹血糖受损患病例数增加85例,空腹血糖受损患病率由14%增至25%,两者比较差异有统计学意义(χ2=88.3,P<0.05);正常糖耐量由57.9%降至46.9%,两者比较差异有统计学意义(χ2=48.2,P<0.05)。空腹血糖5.6～6.0mmol/L组与<5.6mmol/L组及与6.1～6.9mmol/L组比较,在超重或肥胖、高血压、高血脂、脂肪肝及心电图异常方面比较,P<0.05。结论本地区IGR患者分布显著受空腹血糖受损切点下调影响,对于新增单纯空腹血糖受损人群应及早进行干预或治疗。

Objective To explore the change of prevalence distribution of impaired glucose regulation （IGR） after lowering the cut-point of impaired fasting glucose （IFG）. Methods 784 healthy people with physical examination were divided according to the fasting plasma glucose to analyze the change of IGR distribution. Results After lowering the cut-point of IFG, the incidence of IFG increased from 14% to 25% （χ2 = 88.3, P 〈0.05）; the normal glucose tolerance decreased from 57.9% to 46.9% （χ2 = 48.2, P〈0.05）. Compared with FBG 5.6 - 6.0 mmol/L group, both FBG 〈5.6 rnmol/L group and 6.1 - 6.9 mmol/L group had significant differences in the overweight or obesity, hypertension, hyperlipidemia, fatty liver, and electrocardiogram abnormality （all P〈0.05）. Conclusions Lowering the cut-point of IFG has significant influence in the prevalence distribution of IGR. The new patients with IGR should be intervened or treated as soon as possible.