益气活血复方联合西药治疗61例冠状动脉慢血流疗效观察

Treatment of Sixty-one Patients with Coronary Slow Flow Phenomenon by Yiqi Huoxue Recipe Combined Western Drugs: a Clinical Research

目的观察益气活血复方联合西药治疗冠状动脉慢血流的临床疗效,为进一步研究提供临床依据。方法将61例冠状动脉慢血流患者,完全随机分成治疗组31例和对照组30例,对照组只给予西医基础治疗,治疗组在西医基础治疗之上加中药益气活血复方,疗程2个月。分别于治疗前和治疗2个月后进行临床症状的观察、心电图检查及左室射血分数(left ventricular ejection fraction,LVEF)测量。结果治疗组中患者的临床症状及心电图明显改善,其有效率均优于对照组(分别为90.32%vs76.67%,87.10%vs73.33%),差异有统计学意义(P<0.05),但LVEF两组间比较,差异无统计学意义(P>0.05)。结论益气活血复方联合西药能改善冠状动脉慢血流患者的临床症状及心电图缺血改变。

Objective To observe the clinical efficacy of treating patients with coronary slow flow phenomenon by Yiqi Huoxue Recipe （YHR） combined Western drugs, thus providing clinical evidence for further studies. Methods Totally 61 patients with coronary slow flow phenomenon were randomly assigned to the treatment group （31 cases） and the control group （30 cases）. Patients in the control group were treated with basic treatment of Western medicine, while those in the treatment group were treated with bas- ic treatment of Western medicine and YHR. The therapeutic course for all was two months. Clinical symp- toms were observed, and electrocardiogram examinations taken, and left ventricular ejection fraction （LVEF） were evaluated before treatment and at two months after treatment. Results Patients＇ clinical symptoms and electrocardiogram examinations were significantly improved in the treatment group. Its ef- fective rate of improved symptoms was 90.32% in the treatment group, superior to that in the control group （76.67%, P 〈0.05）. The effective rate of electrocardiogram examinations was 87.10% in the treatment group, superior to that in the control group （73.33%, P 〈0.05）. But there was no statistical difference in LVEF between the two groups （P 〉0.05）. Conclusion YHR combined Western drugs could improve clinical symptoms and electrocardiographic ischemia in patients with coronary slow flow phenomenon.