核质转运通路及其抑制剂在肿瘤靶向治疗中的研究进展
摘要
0引言恶性肿瘤是世界范围内死亡率较高的疾病,并有逐年上升的趋势。尽管近年来不断涌现出新的抗肿瘤药物,但肿瘤的高复发性和耐药性仍不可避免肿瘤细胞的恶性增殖与一系列信号转导通路的异常激活或抑制密切相关。其中转录因子及转录辅助因子,通过核孔复合体(nuclear pore complexes,
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
2013年第6期517-520,共4页
Cancer Research on Prevention and Treatment
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