7Kerb R. Implications of genetic polymorphisms in drug trans porters for pharmacotherapy. Cancer Letters, 2006, 234 4-33.
8Jorgensen R. Altered gene expression in plants due to trans interactions between homologous genes. Trends Biotechnol, 1990,8 : 340-344.
9Guo S, Kempheus KJ. Par21, a gene required for establishing polarity in C. elebans embryos, encodes a putative Ser/ Thr kinase that is asymmetrically distributed. Cell, 1995, 81: 611-620.
10Fire A, Xu S, Montgomery MK, et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature, 1996,391 : 806-811.
1Rosenberg L. Treatment of pancreatic cancer: promises and prob- lems of tamoxifen, somatostatin analogs, and gemcitabine[J]. Int J Pancreatol, 1997,22(2) :81-93.
2Siegel R, Ma J, Zou Z, et al. Cancer statistics, 2014[J]. CA Cancer J Clin, 2014,64( 1 ) :9-29.
3Michl P, Gress TM. Current concepts and novel targets in ad- vanced pancreatic cancer[ J ]. Gut, 2013,62 ( 2 ) :317-326.
4Fang X, Thornton C, Scheffler BE, et al. BenzoN3 pyrene decrea- ses global and gene specific DNA methylation during zebrafish de- velopment[ J]. Environ Toxicol Pharmacol, 2013,36( 1 ) :40-50.
5Wohlhueter RM, Mcivor RS, Plagemann PG. Facilitated transporl of uracil and 5-fluorouracil, and permeation of omtic acid into cul- tured mammalian cells [ J ]. J Cell Physiol, 1980, 104 (3) : 309 -319.
7lshida S, Lee J, Thiele DJ, et al. Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctrl in yeast and mammals [ J ]. Proc Natl Acad Sci USA, 2002, 99 ( 22 ) : 14298-14302.
8Ummat A, Rechkoblit O, Jain R, el al. Stnlctural basis fir cispla- tin DNA damage tolerance by human polymcrase eta during cancer chemotherapy [ J ]- Nat Struct Mol Biol, 2012,19 ( 6 ) :628-632.
9Kelland 1,. The resurgence of platinum-based cancer chemotherapy [J]. Nat Rev Cancer, 2007,7(8) :573-584.
10Morgan MA, Parsels LA, Maybaum J, et al. hnproving gcmcit- abine-mediated radionsitization using molecularly targeted Ihera- or, a review[ J]. Clin Cancer Res, 2008,14(21 ) :6744-6750.
