SPGR-T_2~*WI鉴别颅内出血和钙化的定量分析

Quantitative analysis of differential diagnosis between cerebral hemorrhage and calcification by using MR SPGR-T_2~*WI sequence

目的:研究扰相梯度双回波T2*加权成像(SPGR-T2*WI)序列诊断与鉴别诊断颅内出血和钙化的定量分析指标。方法:以多回波采集重度T2*WI三维梯度回波序列(ESWAN)作为金标准,对已确诊脑出血的18例38个病灶和颅内钙化7例11个病灶进行磁共振SPGR-T2*WI(15/30ms)检查。测量不同病灶T2*值,进行统计学分析比较。结果:SPGR-T2*WI序列对于血肿的发现率为CT的1.9倍,对微出血及脑干、小脑等部位出血SPGR-T2*WI比CT检查更有优势。出血(核心区)与钙化的T2*值有明显的统计学差异(P<0.05),但是出血(外周区)与钙化的T2*值无明显的统计学差异(P>0.05)。结论:SPGR-T2*WI序列上颅内出血和钙化T2*值的定量分析,为实现脑血管病的MR一站式诊断奠定了基础。

The purpose of this study was to investigate the feasibility of the quantitative criterion in differ- ential diagnosis of cerebral hemorrhage and calcification by using SPGR-T2 ＊ WI sequence of MR. Methods：ESWAN taken as ＂golden＂ standard, MR SPGR-T2 ＊ WI with TE of 15ms and 30ms was performed in 18 cases （38 lesions） of cerebral he matoma and 7 cases （11 lesions） of calcification. The T2 ＊ value of the same dark area was measured at different TEs. The imaging findings were compared with SPGR-T2 ~ WI and CT. Results：The detecting rate of SPGR-T2 ＂ WI of cerebral hem- orrhage was 1.9 times the rate of CT. Microbleeds and the cerebral hematoma which located in the brain stem and cerebel- lum were easily found by using SPGR-T2 ＊ WI than CT. The T2 ＂ value at different TE values was statistically different at the hematoma （core area） and calcification （P^O. 05） of group cerebral hemorrhage. The T2 ＊ value at different TE values was not statistically different between group of cerebral hemorrhage （peripheral area） and calcification （P〉0.05）. Conclu- sion：The quantitative analysis of acute cerebral hematoma and calcification is available by measuring the T2 ＊ value at differ- ent TE values. It would do contribute to a one-shot diagnosis of cerebrovascular disease.