肿瘤科医务人员对肿瘤相关急性肾损伤认识的调查

A survey on knowledge of acute kidney injury associated with malignancies in Chinese oncology healthcare providers

目的:了解目前肿瘤科医务人员对肿瘤相关急性肾损伤(acute kidney injury,AKI)的认知情况。方法:于2012年9—12月对全国多省市多家三级及二级医院肿瘤科医务人员进行问卷调查,了解其对肿瘤相关AKI知识的认识情况。共收回346份有效问卷用于研究分析。结果:被调查医务人员对易发生AKI的肿瘤类型的认识情况与不同类型肿瘤相关AKI的发生率相符,30.6%的医务人员估计肿瘤患者AKI的发生率与国外临床研究相符;只有11.0%的医务人员能够了解2005年新的AKI定义,82.9%的医务人员能够做到早期请专科会诊。调整化疗药物依据中各选项正确率波动于30.9%～56.9%,AKI预防和治疗措施各选项正确率波动于43.4%～65.3%。对AKI危险因素和发生机制的认识正确率波动于19.7%～50.9%,对4类易并发AKI的化疗药物的认识率波动于12.1%～69.4%,对化疗时易加重AKI的4类药物认识率波动于27.7%～46.0%。医务人员年龄越小,其对AKI的认识正确率越高;而综合医院肿瘤科医务人员的认识正确率普遍高于肿瘤专科医院的医务人员。结论:目前我国医务人员对肿瘤相关AKI的认识尚有不足,需进行相关教育。

To survey the current recognition of AKI （acute kidney injury） associated with malignancies in Chinese oncology healthcare providers. Methods： A questionnaire survey was conducted in Chinese oncology healthcare providers from department of oncology of secondary and tertiary hospitals in different provinces and municipalities in China to investigate their knowledge about tumor- associated AKI. A total of 346 valid questionnaires having complete data were returned and analyzed. Results： The knowledge of tumor types associated with AKI was corresponded with the incidence of AKI in different types of tumors. Of the 346 responders, 30.6% estimated the incidence rate of tumor-associated AKI was in coincidence with the result of foreign researchers; and only 11.0% learned the new definition of AKI issued in 2005. 82.9% of participants could make a demand of nephrological consultation in time. The rates of accurate responses to adjustment recommendations for chemotherapeutic agents were from 30.9% to 56.9%, and the rates of accurate responses to making decision on preventive and therapeutic protocols for AKI were from 43.4% to 65.3%. The rates of accurate recognition of the risk factors and the mechanism of AKI ranged from 19.7% to 50.9%; and for the recognition of four types of chemotherapeutic agents having the potential to cause toxicity, the rates of response ranged from 12.1% to 69.4%. The rates of recognition of 4 different types of chemotherapeutic agents which may aggravate nephrotoxicity ranged from 27.7% to 46.0%. The younger the oncology healthcare providers were, the higher the proper rates of understanding for AKI were. The understanding level of participants in the general hospitals was higher than that in the cancer hospitals. Conclusion： At present, the knowledge on AKI associated with malignancies in Chinese oncology healthcare providers is still inadequate, and it is necessary to perform education on AKI in them.