不同性别青年胃癌患者的临床病理特点分析

Analysis of Clinicopathological Characteristics of Gastric Cancer of Young Patients with Different Gender

目的探讨不同性别青年胃癌患者的临床病理特点。方法回顾性分析78例不同性别住院青年胃癌患者的临床病理特点。结果不同性别青年胃癌患者临床表现、肿瘤部位、分型、TNM分期、生存率差异无统计学意义(P均>0.05),组织学类型中高中分化腺癌和低分化腺癌差异有统计学意义(P<0.05)。结论不同性别青年胃癌患者共同特点为临床表现缺乏特异性,多发生于胃体和胃窦部,分型以浸润溃疡型和弥漫浸润型为主,TNM分期以Ⅲ～Ⅳ期多见,长期生存率低;不同点为青年胃癌患者女性更多见,平均发病年龄偏小,病理类型男性以高中分化腺癌和低分化腺癌多见,女性以低分化腺癌为主。

Objective To explore the clinicopathological characteristics of gastric cancer of young patients with different gender. Methods The clinicopathological characteristics of gastric cancer of 78 young in-patients with dif- ferent gender were reviewed retrospectively. Results There were no differences between the young male patients and the young male patients with gastric cancer, including clinical features, tumor location, parting, TNM stage, survival rate. There were statistical differences between young male patients and young male patients with gastric cancer, including well or moderately differentiated, poorly differentiated. Conclusion Gastric cancer of young patients with different gender have no clinical specificity, mainly occurred in gastric body and antrum, focused on TNM stage Ⅲ and Ⅳ, and have lower long-term survival rate. Young patients appeared more in the female, the mean onset age was younger. Pathologic types focused on well or moderately and low differentiated adenocacinoma in the male, low differentiated adenocacinoma in the female .