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多西他赛联合顺铂治疗晚期头颈部肿瘤的疗效观察 被引量:10

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摘要 目的观察多西他赛联合顺铂治疗晚期头颈部肿瘤的近期疗效和毒副反应。方法 64例晚期头颈部肿瘤患者采用多西他赛联合顺铂治疗,化疗结束后2周评价疗效及毒副反应。结果初治组26例患者中CR 4例,PR 10例,SD 7例,PD 5例,总有效率为53.85%;复治组38例患者中CR 8例,PR 13例,SD 11例,PD 6例,总有效率为55.26%;2组近期疗效比较差异无统计学意义(P>0.05)。毒副反应主要表现为骨髓抑制、胃肠道反应等。结论多西他赛联合顺铂治疗晚期头颈部肿瘤近期疗效较好,毒副反应小,是安全可行的治疗方案。
出处 《肿瘤基础与临床》 2013年第3期243-244,共2页 journal of basic and clinical oncology
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  • 1管忠震,徐瑞华.奈达铂临床研究进展[J].中国肿瘤临床,2004,31(13):774-780. 被引量:176
  • 2邓立力,陈广洲.肺癌患者应用新一代铂类抗肿瘤药物过程中心理健康和生活质量的变化[J].中国临床康复,2005,9(12):70-72. 被引量:16
  • 3王华,王秀美,叶丽华,贡丽霞,韦溶澄.多西紫杉醇联合奈达铂治疗复发卵巢上皮癌临床研究[J].山东医药,2007,47(13):62-62. 被引量:6
  • 4Desoize B,Madoulet C.Particular aspects of platinum compounds used a present in cancer treatment[J].Crit Rev Oncol Hematol,2002,42 (3):317-325.
  • 5Takaoka E,Kawai K,Ando S,et al.Neutropenic colitis during standard dose combination chemotherapy with nedaplatin and irinotecan for testicularcancer[J].JpnJ Clin Oncol,2006,36 (1):60-65.
  • 6Leong SS, Wee J, Tay MH, et al. Paclitaxel, carboplatin, and gemcitabine in metastatic nasopharyngeal carcinoma:a phase Ⅱ trial using a triplet combination [ J ]. Cancer, 2005,103 (3) :569.
  • 7Chan AT, Hsu MM, Goh BC, et al. Muhicenter, phase Ⅱ study of cetuximab in combination with carboplatin in patients with recurrent or metastatic nasopharyngeal carcinoma [J]. J Clin Onco1,2005,23 ( 15 ) :3568.
  • 8Chan AT, Hsu MM, Goh BC, et al. Muhicenter, phase Ⅱ study of cetuximab in combination with carboplatin in pa- tients with recurrent or metastatic nasopharyngeal carcinoma [J].J Clin Onco1,2005,23 ( 15 ) :3568.
  • 9Zhang L,Zhang Y, Huang PY, et al. Phase Ⅱ clinical study of gemcitabine in the treatment of patients with acvanced nasopharyngeal carcinoma after the failure of platinum-based chemotherapy [J].Cancer Chemother Pharmaco, 2008, 61 ( 1 ) :33. Epub 2007 Mar 20.
  • 10Garden AS, Harris J, Voke EE, et al. Results of Radiation Therapy Oncology Group 97-03-A randomized phase Ⅱ trial of concurrent radiation and chemotherapy for advanced squa-mous cell carcinomas of the head and neck ; Long-term results and late toxicities[J].Int J Radiat Oncol Biol Phys,2007,69 (10) :S140.

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