排石颗粒联合坦索罗辛治疗体外冲击波碎石后输尿管下段结石的临床疗效

Clinical analysis of Tamsulosin with Paishi granule to treat lower ureteral stones after the therapy of ESWL

目的探讨排石颗粒联合坦索罗辛治疗体外冲击波碎石(extrocorporeal shock wave lithotripsy,ESWL)后输尿管下段结石的临床疗效。方法选取我院输尿管下段结石ESWL术后患者120例,随机分为实验组和对照组各60例,两组患者均饮水2L/d,常规给予抗感染、止血等处理,实验组给予排石颗粒联合坦索罗辛治疗;对照组仅给予排石颗粒治疗。观察结石排出率、碎石后肉眼血尿时间、典型肾绞痛再次发生率及复发率。结果两组的排石率分别为96.67%和85.00%,两组比较差异具有统计学意义(P<0.05)。实验组的碎石后肉眼血尿时间、典型肾绞痛的再次发生率及复发率均低于对照组,两组比较差异具有统计学意义(P<0.05)。两组均无严重不良反应发生。结论排石颗粒联合坦索罗辛能显著提高输尿管下段结石ESWL后的结石排出率,减少碎石后肉眼血尿的时间和再次发生肾绞痛的几率,降低复发率,且安全有效,值得临床推广。

Objective To evaluate the clinical efficacy of Tamsulosin with Paishi granule to treat lower ureteral stones after the therapy of ESWL. Methods 120 patients with lower ureteral stones in our hospital were chosen. They were divided into the experiment group （60 patients） and the control group （60 patients） randomly. All patients were drinking 2L/d, conventional anti-infection, hemostasis treatment. The patients in the experiment group took orally Tamsulosin matching with Paishi granule while the patients in the control group took orally Paishi granule only. Observed the exclusion rate of the lower ureteral stones, hematuria time,the recurrence of renal colic and the lower ureteral stones. Results The exclusion rates of the lower ureteral stones of two groups were 96.67% and 85.00% respectively. There were significant difference between them （P＆lt;0.05）. The hematuria time,the recurrence of renal colic and the lower ureteral stones in the experiment group were lower than that in the control group. There were no significant adverse reactions in them. Conclusion Tamsulosin with Paishi granule can improve the exclusion rate of lower ureteral stones after ESWL, reduce the gross hematuria time, reduce the recurrence of renal colic and lower ureteral stones, is worthy of being extended in clinical application.