血清超敏C反应蛋白在急性脑梗死中的临床应用

Clinical application of the serum C-reactive protein in acute cerebral infarction

目的探讨急性脑梗死患者血清中超敏C反应蛋白(hs-CRP)在临床的应用。方法选取2011年5月～2012年7月在神经内科住院的急性脑梗死患者129例(脑梗死组),同期健康体检者105例作对照(对照组),检测血清hs-CRP水平并对比分析。结果与正常对照组相比,急性脑梗死组hs-CRP水平明显高于对照组,两组比较差异有统计学意义(P<0.01)。急性脑梗死组梗死面积大小和神经功能损害的程度与hs-CRP的含量呈正相关。结论 hs-CRP是脑梗死重要的独立的危险因子,可以作为急性脑梗死患者诊断和评估病情轻重的指标。

Objective To study the clinical application of the serum C reactive protein in acute cerebral infarc- tion. Methods 129 patients with acute cerebral infarction, who were hospitalized in our neurology department from May 2011 to July 2012,were selected as the Acute Cerebral Infarction Group （ACI group）. 105 peope, who were proved to be heathhy in physical examination, were selected as the control group. Detect their serum C reactive protein levels（hs CRP） and give a comparative analysis of them. Results The serum creactive protein level of the ACI Group was obviously higher than that of the control group. The difference was statistically significant （ P〈0. 0 1 ） .The cerebral infarction area and neurological deficit of the ACI Group were positively related to their CRP level. Conelusion The serum C reactive protein is an important and independent risk factor for acute cerebral infarction. It can be an index for diagnosing and evaluating the condition of patients with acute cerebral infarction.