期刊文献+

姜黄素的抗炎特性及其在肾脏疾病中作用机制的研究进展 被引量:2

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摘要 姜黄素(curcumin)是一种在传统医学中广泛应用的天然多酚,是从姜黄根茎中提取的姜黄磺胺类疏水多酚。姜黄根包含三种最主要的姜黄素类:姜黄素、脱甲氧基姜黄素及双脱甲氧基姜黄素。姜黄中最具有活性成分的姜黄素占77%,而另外二种成分分别占17%和3%。
作者 尤燕舞
出处 《右江医学》 2013年第3期434-436,共3页 Chinese Youjiang Medical Journal
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参考文献16

  • 1王旗,王夔.姜黄素的代谢研究[J].中国药理学通报,2003,19(10):1097-1101. 被引量:49
  • 2刘安昌,娄红祥,赵丽霞.姜黄素在大鼠体内的代谢研究[J].上海中医药杂志,2008,42(8):74-77. 被引量:19
  • 3Goel A, Boland CR, Chauhan DP. Specific inhibition of eyclooxygenase-2 (COX-2) expression by dietary curcu- rain in HT-29 human colon cancer cells[J]. Cancer Lett, 2001,172(2) .. 111-118.
  • 4Surh YJ,Chun KS, Cha HH, et al. Molecular mecha- nisms underlying chemopreventive activities of anti-in- flammatory phytochemicaIs: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation [J]. Murat Res,2001,480-481(11) :243-268.
  • 5Chan MM, Huang HI,Fenton MR, et al. In vivo inhibition of nitric oxide synthase gene expression by eureumin, acancer preventive natural product with anti-inflammatory properties[J]. Biochem Pharmacoh 1998,55 ( 12 ) : 1955- 1962.
  • 6Sarkar FH, Li Y. Cell signaling pathways altered by natu- ral chemopreventive agents[J]. Mutat Res, 2004,555 ( 1- 2) :53-64.
  • 7Aggarwal BB. Signalling pathways of the TNF superfami- ly:a double-edged sword[J]. Nat Rev Immunol, 2003,3 (9) :745-756.
  • 8Shishodia S, Amin HM, Lai R, et al. Curcumin (diferu- loylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and in- duces apoptosis in mantle cell lymphoma [J]. Biochem Pharmacol, 2005,70 (5) : 700-713.
  • 9吴迪英,郭闻渊,张豪杰,蔡旭东,徐鹏杰.姜黄素对小鼠肾脏再灌注损伤的保护作用及其机制研究[J].解放军医学杂志,2012,37(7):671-675. 被引量:6
  • 10王光新,李朝芝,夏瑗瑜,余福安.缺血时间对肾脏肿瘤坏死因子-α的影响及姜黄素预处理的实验研究[J].中国中西医结合肾病杂志,2012,13(11):988-990. 被引量:2

二级参考文献57

  • 1朱方强,江军,黄宏.姜黄素抑制内毒素所致小鼠急性肾功能损害的作用[J].第三军医大学学报,2005,27(11):1074-1077. 被引量:13
  • 2Wang YJ, Pan MH, Cheng AL et al. Stability of curcumin in buffer solutions and characterization of its degradation products. J Pharmaceu & Biomed Analysis, 1997 ; 15 (12) : 1867-76.
  • 3Oetari S, Sudibyo M, Commandeur Jan NM et al, Effects of curcumin on cytochrome p450 and glutathione S-transferase activities in rat liver. Biochem Pharmacol, 1996,51(1) : 39-45.
  • 4Wahlstrom B, Blennow G. A study on the fate of curcumin in the rat. Acta Pharmacol Toxicol, 1978;43(2) :86-92.
  • 5Holder GM, Plummer JL, Ryan AJ. The metabolism and excretion of curcumin ( 1,7-his-( 4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) in the rat. Xenobiotica, 1978;8(12):761-8.
  • 6Ravindranath V, Chandrasekhara N. Absorption and tissue distribution of curcumin in rats. Tozicology, 1980;16 (3): 25965.
  • 7Ravindranath V, Chandrasekhara N. Metabolism of curcuminstudies with [^3 H]curcumin. Toxicology, 1982; 22 : 337 - 44.
  • 8Ravindranath V, Chandrasekhara N. In Vitro studies on the intestinal absorption of curcumin in rats. Toxicology, 1981;20(2-3): 251-7.
  • 9Shoba G, Joy D, Joseph T et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers.Planta Medica , 1998;64:353-6.
  • 10Pan MH, Huang TM, Lin JK. Biotransformation of curcumin through reduction and glucuronidation in mice. Drug Metabolitism & Disposition, 1999;27(4) :486-94.

共引文献71

同被引文献37

  • 1张迪亚,陈莉丽.牙龈卟啉单胞菌脂多糖引起牙周炎症的机制和特点[J].国外医学(口腔医学分册),2005,32(6):455-457. 被引量:2
  • 2周业庭,钱建民.P-糖蛋白和p38在人肝癌组织中的表达及其意义[J].中华实验外科杂志,2007,24(5):622-623. 被引量:4
  • 3Taubman M A,Valverde P,Han X,et al.Immune response:the key to bone resorption in periodontal disease[J].J Periodontol,2005,76(11 Suppl):2033-2041.
  • 4Zhao F,Gong Y,Hu Y,et al.Curcumin and its major metabolites inhibit the inflammatory response induced by lipopolysaccharide:Translocation of nuclear factor-κB as potential target[J].Molecular Medicine Reports,2015,11(4):3087-3093.
  • 5Biswas S,Rahman I.Modulation of steroid activity in chronic inflammation:a novel anti-inflammatory role for curcumin[J].Mol Nutr Food Res,2008,52(9):987-994.
  • 6Hanai H,Sugimoto K.Curcumin has bright prospects for the treatment of inflammatory bowel disease[J].Curr Pharm Design,2009,15(18):2087-2094.
  • 7Bainbridge B W,Darveau R P.Porphyromonas gingivalis lipopolysaccharide:an unusual pattern recognition receptor ligand for the innate host defense system[J].Acta Odontol Scand,2001,59(3):131-138.
  • 8Bergamini A,Bolacchi F,Bongioyanni B,et al.Granulocyte–macrophage colony-stimulating factor regulates cytokine production in cultured macrophages through CD14-dependent and-independent mechanisms[J].Immunology,2000,101(2):254-262.
  • 9Waraaswapati N,Chayasadom A,Surarit R,et al.Induction of Toll-like receptor expression by Porphyromonas gingivalis[J].J Periodontol,2013,84(7):1010-1018.
  • 10Ertugrul A S,Sahin H,Dikilitas A,et al.Comparison of CCL28,in-terleukin-8,interleukin-1βand tumor necrosis factor-alpha in subjects with gingivitis,chronic periodontitis and generalized ag-gressive periodontitis[J].J Periodontal Res,2013,48(1):44-51.

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