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脂多糖结合蛋白在原发性胆汁性肝硬化中的检测意义 被引量:1

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摘要 目的探讨原发性胆汁性肝硬化患者脂多糖结合蛋白(LBP)的水平及意义。方法采用酶联免疫吸附技术(ELISA)检测58例原发性胆汁性肝硬化患者中LBP水平,伴有腹水的患者同时测定LBP水平并记录2个月后的存活情况。结果原发性胆汁性肝硬化患者的LBP水平显著高于健康者(P<0.05),伴腹水肝硬化患者LBP水平显著高于无腹水肝硬化患者(P<0.05);Child-PughB级和C级患者腹水LBP差异无统计学意义(P>0.05),但B级患者血浆LBP显著高于C级患者(P<0.05)。结论 LBP在原发性胆汁性肝硬化患者中水平升高,LBP的升高可能是一种持续的慢性免疫应答。
出处 《河北医药》 CAS 2013年第12期1810-1811,共2页 Hebei Medical Journal
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