摘要
对含氟杀虫剂溴虫腈的四条合成路线进行了比较。重点介绍了以对氯苯甲醛 ,氰化钠等制得 2 对氯苯基甘氨酸 ,再经三氟乙酸化 ,2 氯丙烯腈环化、溴化 ,最后与氯甲基乙醚反应制得产物的路线。其总收率为 50 % (以对氯苯甲醛计 )。
Four synthesis processes of chlorfenapy were compared. Studies were focused on the route with 4 chlorobenzaldehyde and sodium cyanide as raw materials. The total yield reached to 50% (based on 4 chlorobenzaldehyde).
