凝血酶与雷尼替丁治疗新生儿上消化道出血疗效观察

Clinic Observation on the Thrombin and Ranitidine for New born Hemorrhage of Upper Digestive Tract

目的 :为了解凝血酶与雷尼替丁在新生儿上消化道出血的疗效。方法 :将新生儿上消化道出血 5 8例随机分成治疗组和对照组 ,两组的原发病综合治疗相同 ,治疗组 30例 ,胃内注入凝血酶及雷尼替丁作局部治疗。结果 :治疗组止血显效率 (93.3% )明显高于对照组 (4 2 .9% ) ,平均止血时间 [(34.2± 10 .46 ) h]明显短于对照组 [(5 0 .5 7± 10 .85 ) h],两组比较有非常显著性差异 (P<0 .0 0 1)。结论

Objective:To observate the effects of Thrombin and Ranitidine for New born hemorrhage of upper digestive tract.Methods:58 cases New born hemorrhage of upper digestive tract were divided randomly to 30 cases treatment group with adding Thrombin and Ranitidine by endogastric infusion and 28 cases controls.Results:The hemostatic rate of the treatment group was higher significantly(93.3%) than those of controls(42.9%),and homostatic mean time of the treatment group was shorter significantly[(34.2±10.46)h] than those of controls[(50.57±10.85)h] ( P <0.001).Conclusion:Thrombin and Ranitidine were effective drugs for treatment of new born hemorrhage of upper digestive tract.