风湿病的药物治疗

Therapeutic Drugs for Rheumatic Diseases

非甾体抗炎药的使用因其不良反应而逐渐减少 ,本文分类介绍了若干风湿病药物疗法及可能产生的副作用。新开发的环氧酶 2抑制剂及生物技术药物不仅可减少胃肠道副作用 ,对风湿病的早期治疗有良好疗效 ,且可减少关节炎引起的功能丧失 ;临床实践表明联合用药优于单药治疗 ,既提高了疗效 ,又减少了副作用。

Now the clinical application of nonsteroidal antiinflammatory drugs is getting less and less because of their adverse events. In this article, a certain number of antirheumatics and the related side effects were introduced. Cyclooxygenase 2 inhibitors and biological products ,which were developed recently, have showed higher therapeutic effect and lower incidence of gastrointestinal side effects, reducing functional loss resulted from rheumatoid arthritis.Furthermore, the clinical researches have proved that the better effects could be achieved by combined treatments.