摘要
目的探讨CEUS在鉴别诊断卵巢良恶性肿瘤中的应用价值。方法纳入因卵巢肿瘤接受手术的患者48例,共51个肿块,于术前1周内行经腹CEUS检查,动态观察肿瘤的造影增强模式,绘制肿瘤ROI时间-强度曲线并获得峰值强度(Imax)、上升时间(RT)、达峰时间(TTP)、平均渡越时间(mTT)及曲线下面积(AUC);比较良恶性肿瘤间各参数差异。结果 51个肿块中,良性肿瘤24个,恶性肿瘤27个;CEUS中良性肿瘤呈均匀增强,恶性肿瘤呈不均匀增强;恶性肿瘤造影剂Imax、AUC和mTT均大于良性肿瘤(P均<0.05),而RT和TTP二者间差异无统计学意义(P均>0.05)。结论 CEUS可准确评价肿瘤内血流灌注特点,在鉴别诊断卵巢良恶性肿瘤中有重要应用价值。
Objective To investigate the value of CEUS in differential diagnosis of benign and malignant ovarian tumors. Methods Totally 48 cases (51 masses) receiving surgery due to ovarian neoplasms were enrolled. Transabdominal CEUS was performed within 1 week before surgery. The enhanced pattern of the tumor was dynamically observed, and the maximal intensity (Imam), rising time (RT), time to peak (TTP), mean transit time (mTT) and area under the curve (AUC) of contrast agent obtained from time-intensity curve were compared between benign and malignant tumors. Results There were 24 benign tumors and 27 malignant tumors. In CEUS, benign tumors showed homogenous enhancement, while malig- nant tumors showed heterogeneous enhancement. I AUC and mTT of contrast agent of malignant tumors were all higher than those of benign tumor (all P〈0. 05), but there was no significant difference of RT nor TTP between benign and malignant tumors (both P〉0. 05). Conclusion CEUS can accurately assess the perfusion characteristics of tumors, there- fore having great application value in differential diagnosis of benign and malignant ovarian tumors.
出处
《中国医学影像技术》
CSCD
北大核心
2013年第6期994-997,共4页
Chinese Journal of Medical Imaging Technology
基金
上海市科委医学引导类科技项目(114119a1000)
关键词
卵巢肿瘤
超声检查
造影剂
时间-强度曲线
Ovarian neoplasms
Ultrasonography
Contrast media
Time-intensity curve