胸腺肽与转移因子治疗儿科常见病的疗效对比观察

Contrastive observation of the effects between thymopeptide and transfer factor for general diseases in pediatrics

目的 探讨胸腺肽 (TP)和转移因子 (TF)治疗儿童常见病的疗效。方法 选择具有细胞免疫功能低下 ,体液免疫功能或补体功能紊乱的反复呼吸道感染 ,反复腹泻 ,自身免疫性疾病 ,免疫复合病 ,病毒感染和细胞内细胞感染等 184例 ,年龄 5月～ 14岁的患儿作为治疗观察对象 ,随机分成两组 ,用药前后检测 E玫瑰环试验 (ERT) ,淋巴细胞转化试验 (CBT) ,免疫球蛋白 (Ig G、Ig M、Ig A) ,补体 (CH5 0 、C3、C4)等实验指标。结果 胸腺肽和转移因子对患者的细胞免疫纠正率分别是 89.2 %、87.9% ,对体液免疫纠正率分别是96 .0 %、82 .6 %。结论 胸腺肽对调整体液免疫功能较好 ,而转移因子主要调节细胞免疫功能 。

Objective To evaluate the treatment of common pediatric diseases through thymopeptide(TP) and transfer factor (TF).Methods 184 child patients (5 months～14 years of age) were chosen and divided randomly into two groups.They suffered from low cellular immune function,inordinate complement and humoral immunity with reinfections of respiratory tract,rediarrbea,immune disease,viral infections of bacteria infections in cell etc.Before and after medication,test indexes were examined about Erosetts test(ERT),lymphocyte transfrmation test (CBT),and the tests of immunoglobulin (IgA,IgM,IgG) as well as complements (CH 50 ,C 3,C 4).Results The redressed rate for patints'cellular immunity were TP-89.2% and TF-87.9% respectively and that for the patients'humoral immunity was TP-96% and TF-82.6% respectively.Conclusion TP in improving humoral immunity is better than TF and TF is mainly used to improve cellular immunity,both without obvious side effects.