绝经后妇女腰椎骨质疏松的定量CT研究

Quantitative CT measurement of lumbar bone mineral density(BMD) in postmenopausal osteoporosis women

目的 研究绝经后妇女不同年龄组腰椎骨密度 (BMD)与骨质疏松关系及临床表现。方法 采用 CT机横断扫描及自制固体标准体模测量 99例绝经后妇女第 2～ 4腰椎上 1 / 3处骨密度 (BMD) ,并对其临床症状进行观察。结果 99例绝经后妇女有 76例被诊断为骨质疏松 ,占 77%。并显示腰椎骨密度 (BMD)随增龄逐渐减低 ,以大于 70岁年龄组骨密度最低 ,骨质疏松最严重 ,平均值 60 .2 mg/cm3 ,方差为 1 8.9,而且 1 0 0 %有不同的临床症状。结论 对绝经后妇女进行 BMD观测是非常有价值的 ,定量 CT方法简便易行 ,对代谢转换率高的松质骨有单独测量的优势 ,敏感地反映了骨量的变化。

To investigate the relationship between the lumbar bone mineral density(BMD) and osteoporosis and the clinical manifestation of postmenopausal wemen.Methods CT scan was used to asses the BMD of L2～L4 of 99 postmenopausal women.Results 76 cases(77%) of the 99 postmenopausal women were diagnosed as osteoporosis. The lumbar BMD decreased as the advance of the age and reached its lowest level in the group older than 70 yr(x=69.2, s=18.9) who suffered from the severest osteoporosis with some sort of clinical manifestations.Conclusions It is valuable to measure BMD in postmenopausal women. QCT is a convenient sensitive measurement of BMD.