10种中药有效成分抑制口腔主要致病菌比较

Comparison of inhibitions to oral bacteria among 10 Chinese herbs

目的 :为评价常见中药对口腔主要致病菌作用及其作为口腔保健用药的可能性。方法 :从文献报导中有抗致龋作用的中草药中选择出 1 0种中药或天然植物进行 1 0种有代表性的口腔致病菌的药敏试验。结果 :茶多酚和鞣酸具有较强的抑菌和杀菌作用。结论 :初步认为茶多酚和鞣酸更适合作为预防和治疗口腔疾病的保健用药。

OBJECTIVE:In order to evaluate the possibility of Chinese herbs as a new drug for preventing caries and periodontitis,the effects of ten extracts of Chinese herbs,including tea polyphenol,tannic acid,magnolol,chlorogenic acid,emodin,alpinetin,gentiopicrin,et al,on the growth of bacteria,which were known as pathogens of caries and periodontitis were determined.METHODS:Sensitive test of bacteria were carried out by dilution method.RESULTS:It indicated that the tea polyphenol and tannic acid could inhibit the bacteria growth more obviously than other herbs.CONCLUSION:Tea polyphenol and tannic acid will probably be a relatively ideal natural agent for oral care product which both decreases incidence of caries and periodontitis and maintains the balance of oral ecology system.