焦虑障碍患者焦虑敏感与特质焦虑的相关研究

Correlation between anxiety sensitivity and trait anxiety of patients with anxiety disorders

目的:探讨焦虑障碍患者焦虑敏感与特质焦虑、临床特征的相关性。方法:68例焦虑障碍患者(焦虑组)根据汉密尔顿焦虑量表(HAMA)评分≥7分为分界值,分为焦虑未缓解组43例和缓解组25例,进行焦虑敏感测定量表(ASI-R)及状态-特质焦虑问卷中特质焦虑量表部份(T-AI)的评定;ASI-R评分结果与70名正常对照(正常对照组)进行比较,分析ASI-R评分与T-AI总分及临床特征的相关性。结果:焦虑组ASI-R总分、对躯体感觉的焦虑因子分、对躯体感觉的恐惧因子分、对认知失控焦虑恐惧因子分、对社会后果焦虑恐惧因子分均高于正常对照组(t分别=8.51,9.00,8.15,8.74,3.24;P均<0.01)。焦虑缓解组ASI-R总分、及对躯体感觉的焦虑因子分、对躯体感觉的恐惧因子分、对认知失控焦虑恐惧因子分均高于正常对照组(t分别=4.41,3.37,4.24,3.76;P均<0.01);未缓解组ASI-R总分及各因子分高于缓解组(t分别=3.30,3.41,2.61,2.78,2.14;P<0.05或P<0.01)。经相关分析,ASI-R总分、及躯体感觉的焦虑因子分、对认知失控的焦虑恐惧因子分与T-AI总分显著相关(r分别=0.33,0.28,0.40;P<0.05或P<0.01);ASI-R总分、对认知失控焦虑恐惧因子分、对社会后果焦虑恐惧因子分与病程显著相关(r分别=0.27,0.26,0.31;P均<0.05)。结论:焦虑障碍患者的焦虑敏感程度高于正常人群;焦虑敏感水平部分与焦虑特质有关。

Objective：To explore the correlation between anxiety sensitivity and trait anxiety,clinical features of patients with anxiety disorders. Method：We investigated 68 patients with anxiety disorder（ anxiety group） and 70 normal individuals（ control group） . The anxiety group was separated into the non-remission group Hamilton anxiety scale（ HAMA） ≥7,n = 43 and the remission group （ HAMA 7,n = 25） . The anxiety group was assessed by anxiety sensitivity index-revised（ ASI-R） ,trait anxiety inventory（ part of state-trait anxiety inventory,TAI） and 70 normal controls with ASI-R. Results：The total scores and the factor scores（ anxiety of somatic sensations,fear of somatic sensations,fear of cognitive dyscontrol,fear of publicly observable anxiety reactions） of ASI-R were all markedly higher in the patients with anxiety disorders than those of the normal controls （ t = 8. 51,9. 00,8. 15,8. 74,3. 24,respectively; all P 0. 01） . The total scores and some factor scores （ anxiety of somatic sensations,fear of somatic sensations,fear of cognitive dyscontrol） of ASI-R were all markedly higher in remission group than those of the normal controls （ t = 4. 41,3. 37,4. 24,3. 76,respectively; all P 0. 01） ,and all markedly lower than the non-remission group （ t = 3. 30,3. 41,2. 61,2. 78,2. 14,respectively; P 0. 05 or P 0. 01） . According to correlation analysis,the total scores of TAI significantly correlated with the total scores of ASI-R and some factor scores（ anxiety of somatic sensations,fear of cognitive dyscontrol） of ASI-R（ r = 0. 33,0. 28,0. 40,respectively; P 0. 05 or P 0. 01） . A significantly positive correlation was found between the course of disease and the total scores and some factor scores（ fear of cognitive dyscontrol,fear of publicly observable anxiety reactions） of ASI-R （ r = 0. 27,0. 26,0. 31,respectively; all P 0. 05 ） . Conclusion：The anxiety sensitivity among patients with anxious disorders are higher than that among normals, which relates to the level of anxiety,and the level of anxiety sensitivity relates to anxiety trait partly.