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急性脑缺血对机体免疫系统的影响 被引量：8

Impact of acute cerebral ischemia on the organism in immune
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摘要 脑缺血引起严重的中枢神经系统的损害已被许多实验证实,然而脑缺血是如何对免疫产生的影响如何却知之甚少。文中通过搜集近年来脑缺血再灌注相关领域的研究文献,总结急性脑缺血对机体免疫系统的影响,旨在为治疗急性脑缺血相关疾病提供免疫学的理论依据。 Cerebral ischemia caused serious damage to the central nervous system has been confirmed by many experiments; however, little is known about the mechanism of cerebral ischemia in immune. We summarized the impact of acute cerebral ischemia on the immune system by gathering some of the research literatures about cerebral ischemia and reperfusion in recent years. This review may provide a theoretical basis for the treatment of acute cerebral ischemia and related diseases.
作者 李茜 陈兴东 段满林
机构地区 南京军区南京总医院疗养区麻醉科 南京军区南京总医院麻醉科
出处 《医学研究生学报》 CAS 北大核心 2013年第6期654-657,共4页 Journal of Medical Postgraduates
关键词 急性脑缺血 免疫 炎性因子 Acute cerebral ischemia Immune Inflammatory factors
分类号 R743 [医药卫生—神经病学与精神病学]
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参考文献32

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  • 2Hotchkiss RS, Strasser A, McDunn JE, et al. Cell death[ J]. N Engl J Med, 2009, 361(16): 1570-1583.
  • 3Kamel H, Iadecola C. Brain-immune interactions and ischemic stroke: clinical implications[J]. Arch Neurol, 2012, 69(5): 576-581.
  • 4Kruger B, Krick S, Dhillon N, et al. Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation[J]. Proc Natl Acad Sci USA, 2009, 106 (9) : 3390-3395.
  • 5Brecht S, Waetzig V, Hidding U, et al. FK506 protects against various immune responses and secondary degeneration following cerebral ischemia [ J ]. Anat Rec ( Hoboken), 2009, 292 ( 12 ) : 1993-2001.
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  • 8Shin JS, Hyun SY, Kim DH, et al. Chronic hypoperfusion in- creases claudin-3 immunoreactivity in rat brain [J]. Neurosci Lett, 2008, 445(2) : 144-148.
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医学研究生学报
2013年 第6期

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