摘要
嗜酸性膀胱炎为一种膀胱增殖性病变,儿童发病罕见,病理表现为膀胱壁各层的嗜酸性粒细胞浸润。嗜酸性膀胱炎病因不明,可能与变态反应有关。发病见于各年龄段,男性多于女性。自1960年首次被报道以来,病例报道300余例,其中儿童70余例。主要临床表现为尿频、尿急、疼痛(耻骨上膀胱区疼痛/尿痛)、血尿(肉眼/镜下)、排尿困难、遗尿等,部分患者存在外周血嗜酸性粒细胞增多。血常规、尿常规、影像学检查、膀胱镜检查为常规检查,确诊依靠病理诊断。嗜酸性膀胱炎儿童患者较成人自限性强,主要治疗方法为联合应用糖皮质激素、抗组胺药物等。当出现严重并发症或病变持续进行性加重时可行手术治疗。
Eosinophilic cystitis(EC) is a kind of bladder proliferation disease and rather rare in children. The pathological character shows invasion of huge amounts of eosinophil granulocytes in the total bladder wall. Although it has unknown etiology, but it is widely believed to be involved in allergy. It can appear at any age with a higher incidence in male. Since it was first reported in 1960,there are a total of more than 300 patients reported,about 70 of them are children. The major clinical manifestations are urinary frequency, suprapubic pain during mietion, gross or microscopic hematuria, dysuria, nocturia and so forth. Some patients with increased eosinophils in the peripheral blood. It is essential to examine blood routine, urine routine,imaging tests and cystoscopy and defining diagnosis depends on histopatbologic biopsy. The self-limiting of EC in children is much stronger. The main therapies for EC are application of corticoste-roids, antihistamines and so forth, while feasible operation should be treated when severe complications appear or the disease progress.
出处
《中华实用儿科临床杂志》
CAS
CSCD
北大核心
2013年第11期868-870,共3页
Chinese Journal of Applied Clinical Pediatrics
基金
国家青年科学基金(30901485)
关键词
嗜酸性膀胱炎
诊断
治疗
尿动力学检查
Eosinophilic cystitis
Diagnosis
Treatment
Urodynamic study