慢性肺心病心力衰竭临床药物治疗分析

Clinical medication treatment analysis of chronic pneumocardial disease combined with cardiac failure

目的探讨慢性肺心痛并发心力衰竭的临床药物治疗方法。方法选取湛江中心人民医院收治的慢性肺心病并发心力衰竭患者90例，将其随机分为观察组和对照组，对照组给予抗感染、消炎、吸氧、利尿以及纠正电解质紊乱等常规治疗，观察组在对照组基础上给予1：2服贝那普利，治疗2个疗程后观察两组患者的心功能改变情况以及不良反应情况。结果观察组总有效率（93．33％）明显高于对照组（66．67％），且心功能改善情况明显优于对照组，观察组pH和PaO2上升程度和PaCO2下降程度明显大于对照组，两组对比差异均有统计学意义（P〈0．05）。观察组出现6例不良反应，对照组未出现不良反应。结论在常规治疗的基础上给予贝那普利治疗慢性肺心病并发心力衰竭可有效改善患者的心功能，且不良反应少均可耐受。

Objective To investigate the clinical medication treatment of chronic pulmonary heart disease with heart failure . Methods Ninety cases of chronic pulmonary heart disease with heart failure were selected, which were randomly divided into observation group and control group, patients in control group were given conventional treatment such as anti-infection, diminish inflammation, oxygen, diuresis and correct electrolyte disorder, patients in observation group were given oral benazepril based on the treatment of control group. After 2 courses of treatment, the cardiac function change condition and adverse reaction conditions were observed. Results The total effective rate of observation group （93.33%） was much higher than that of the control group（66.67% ）, and improvement of heart function was obviously superior to the control group, the pH and PaO2 rising degree and PaCO2 de- creasing degree of observation group was significantly greater than those in control group, the differ- ences between the two groups were significant（ P 〈 0.05 ）. In the observation group, 6 cases had adverse reactions, while no adverse reaction occurred in control group. Conclusions Benazepril on the basis of conventional treatment in the treatment of chronic pulmonary heart disease combined with heart failure can effectively improve cardiac function of patients, and has less adverse reactions, all patients can tolerate.