术前肌肉注射苯巴比妥钠对老年患者全身麻醉苏醒期的影响

Effect of phenobarbital sodium on the aged patients during recovery from general anesthesia

目的探讨麻醉前应用药苯巴比妥钠对老年患者全身麻醉效果的影响。方法50例限期膀胱癌病灶切除患者随机分成两组（n=25）：I组不用苯巴比妥钠，Ⅱ组应用苯巴比妥钠。麻醉前用镇静／警觉评分标准（OAA／S）观察和评估患者的意识和神志状态并抽血化验血清皮质醇浓度。术毕记录两组恢复期躁动发生率，睁眼时间、拔管时间和定向力恢复时间。结果两组患者的意识和神志状态及血清皮质醇浓度比较差异无统计学意义（P〉0．05）。Ⅱ组患者术毕恢复期躁动发生率高，睁眼时间、拔管时间和定向力恢复时间长（P〈0．05）。结论麻醉前应用苯巴比妥钠可使全身麻醉老年患者的苏醒质量下降。

Objective To investigate the effect of phenobarbital sodium before anesthesia on general anesthesia effect of aged patients. Methods Fifty patients with bladder cancer resection within the lesions were randomly divided into two groups （n = 25 ） ： phenobarbital sodium was not given in group I , phenobarbital sodium was applied in group Ⅱ. The patients＇ consciousness and mind state with calm/alert score standard（OAA/S） before anaesthesia were observed and appraised, and the serum cortisol concentration was tested. Moving restlessly rate in recovery period, eye open time, drawing tube time and directional power recovery time of both groups were recorded after operation. Results There was no significant difference in state or consciousness or serum cortisol concentration between the two groups （P 〉 0. 05）. In group Ⅱ, the recovery period moving restlessly rate after operation was higher, the open time, drawing tube time and directional power recovery time were longer than those in group I （P 〈 0. 05 ）. Conclusions Using phenobarbital sodium before anaesthesia should decrease the quality of resuscitation for aged patients who received general anesthesia.