非离子型对比剂在新生儿上消化道造影检查中的应用

Clinical Application of the Non-Ionic Contrast Medium in Contrast Examination of Upper Gastrointestinal Tract in Newborn

目的探讨碘海醇在新生儿消化道造影检查中对消化道疾病诊断的应用价值。方法对临床拟诊消化道畸形而无法进行上消化道钡餐检查的31例患儿采取口服或胃管给碘海醇的方法行消化道病变的检查。结果消化道畸形26例(3例食管闭锁,2例食管裂孔疝,5例先天性肥厚性幽门狭窄,5例十二指肠闭锁,6例环状胰腺,3例肠旋转不良,2例空肠闭锁),3例吞咽功能紊乱,2例特发性胃扭转伴胃食管返流,其中手术26例。结论口服碘海醇消化道造影检查,可以拓宽消化道检查的范围,弥补消化道钡剂检查的不足,是一种安全、可靠、可广泛应用于临床检查的方法。

Objective To evaluate the efficiency of the Iohdexol in upper digestive tract contrast examination for diag-nosing congenital digestive tract malformation of newborn. Methods 31 patients （19males and 12 females, age range 12 hour to 30 day） with congenital digestive tract malformation were included in the study. Iohexol was administrated orally or through gastric canal for upper digestive tract contrast examination. Results Among 31 newborns, congenital digestive tract malformations were found in 26, included stomach volvulus with gastroesophageal reflux in 2 cases; disturbance of swallowing function in 3 ; esophageal atresia in 3 ; esophageal hiatal hernia in 2 ; congenital hypertrophic pyloric stenosis in 5 ; duodenal atresia in 5 ; annular pancreas in 6 ; malrotation of intestine in 3 ; jejunal atresia in 2 cases. Conclusion Io-hexol contrast examination retrieves the insufficient of the barium meal examination for digestive tract. It＇ s a safe and relia- ble method in the diagnosis of congenital digestive tract malformation in newborns.