超声造影在伴有微钙化的甲状腺结节中的诊断价值

Value of contrast-enhanced ultrasonography in the diagnosis of microalcified thyroid nodules

目的探讨超声造影在鉴别伴有微钙化的甲状腺结节良恶性中的诊断价值。方法对92例经手术病理证实的伴有微钙化的甲状腺结节患者行超声造影检查,评估超声造影判断其良恶性的敏感性、特异性、阳性预测值、阴性预测值及诊断符合率。结果注入造影剂后,59个恶性结节中,54个表现为不均匀弱增强,4个为等增强,1个呈高增强;33个良性结节中,26个呈均匀等增强,3个呈均匀高增强,4个呈不均匀弱增强;良恶性结节的超声造影增强程度比较差异有统计学意义(P<0.05)。超声造影诊断伴有微钙化的甲状腺结节良恶性的敏感性、特异性、阳性预测值、阴性预测值及诊断符合率分别为91.53%、87.88%、93.10%、85.29%及90.22%。结论超声造影对伴有微钙化的甲状腺结节的良恶性具有较高的诊断价值。

Objective To evaluate the value of contrast-enhanced ultrasound（CEUS） in the diagnosis of microcalcified thyroid nodules. Methods Ninety-two patients with microcalcified thyroid nodules which were confirmed by operation and pathology underwent CEUS.The sensitivity,specificity,positive predictive,negative predictive and diagnostic coincidence rate of CEUS were evaluated. Results After contrast agent injection, 54 of 59 malignant thyroid nodules exhibited uneven weak enhancement, 4 nodules showed equal enhancement and one nodules appeared high enhancement. Among 33 benign thyroid nodules, 26 of them exhibited even equal enhancement, 3 nodules showed even high enhancement and 4 nodules appeared uneven weak enhancement. The sensitivity,specificity,positive predictive value,negative predictive value and diagnostic coincidence rate of CEUS were 91.53%, 87.88%, 93.10%, 85.29%, 90.22%, respectively. Conclusion CEUS has higher value in the differential diagnosis of benign and malignant mierocalcified thyroid nodules.