腹膜后孤立性纤维瘤的CT表现(附2例报道并文献复习)

CT imaging features of retroperitoneal solitary fibrous tumor(report of 2 cases and literature review)

目的探讨腹膜后孤立性纤维瘤的CT影像学特征。方法回顾性分析2例经病理证实的腹膜后孤立性纤维瘤的CT影像学表现,并与病理组织学结果作对照分析。结果腹膜后孤立性纤维瘤的CT表现为巨大的境界清楚的肿块,由两种不同密度的实质成分组成,增强扫描显著强化,动脉期瘤内可见肿瘤血管影,静脉期肿瘤持续强化,并可见强化的包膜。病理学检查肿瘤细胞呈梭形,间质为增生的胶原纤维,肿瘤由细胞密集区和细胞疏松区组成,免疫组化示CD34阳性。结论腹膜后孤立性纤维瘤的CT影像学表现具有一定的特征性,病理形态学及免疫组织化学检查可以明确诊断。

Objective To investigate the CT imaging features of retroperitoneal solitary fibrous tumor （SFT）. Methods CT findings in 2 cases with SFT confirmed by histopathology and immunohistochemistry were reviewed retrospectively, and compared with pathological results. Results CT findings of retroperitoneal SFT were large, well defined and smooth contour of masses and it was consisted of solid components of two different density. On enhanced CT scans, tumors showed strongly enhancing, the multiple vascular shadows were seen within the tumor in arterial phase. There was progressive enhancement from the arterial to venous phase, and capsule of tumor can he displayed. Histologically, the tumors were composed of spindle ceils within a background of collagen stroma, and showed a wide range of growth patterns, alternating hypercellular （tumor cell rich） and hypocellular （collagen-rich） areas. The diagnosis was confirmed by characteristic positive immunohistochemical staining for CD34. Conclusion The retroperitoneal SFT possesses a definite characteristic in CT imaging findings, the diagnosis is depended on histopathology and immunohistochemistry.