肝纤维化的磁共振成像研究进展

Research progress in MR imaging of liver fibrosis

肝活检组织学检查作为肝纤维化的诊断及评价严重程度的标准。肝纤维化分期决定治疗的预后和方法的选择。但是,肝活检具有一定创伤,存在取样误差以及难以重复检查。磁共振成像已经成为评价肝纤维化越来越重要的影像技术。本文就目前临床应用及最新的无创评价肝纤维化的磁共振成像进行综述。

Currently, the reference standard for diagnosing and assessing the severity of liver fibrosis is biopsy with his tologic analysis. The stage of liver fibrosis is used to determine the prognosis and the treatment options. However, liver biopsy is relatively invasive, limited by sample size, and difficult to repeat. Thus, accurate noninvasive methods for staging liver fibrosis are necessary. Magnetic resonance （MR） imaging has become an increasingly important imaging technique in the evaluation of liver fibrosis. In this article, we will review the research progress in state of the-art MR imaging based techniques in current practice and in development for noninvasive assessment of liver fibrosis.