肝病患者血清胆碱酯酶检测临床意义分析

Clinical significance of serum cholinesterase detection in patients with liver disease

目的探讨肝病患者检测血清胆碱酯酶(ChE)的临床意义。方法检测肝病患者112例(实验组)和健康者106例(对照组)血清ChE活性。结果各肝病患者组与对照组检测结果比较差异有统计学意义(P<0.05)。结论肝病患者血清ChE活性低于健康者,并随肝病病情加重而逐渐下降;血清ChE活性能较好反映肝脏合成功能,准确反映肝病患者病情严重程度。

Objective To explore the significance of serum cholinesterase （ChE） detection in patients with liv- er disease. Methods 112 patients with liver disease （experimental group） and 106 healthy subjects （control group） were enrolled and detected for serum ChE activity. Results There were significant differences of ChE activity be- tween patients with various liver diseases and healthy subjects （P〈0.05）. Conclusion ChE activity in patients with liver disease could be lower than healthy subjects and, with the increasing of disease severity,ChE activity might be gradually decreased. Serum ChE activity could reflect hepatic synthetic function and accurately reflect the severity of liver disease.