注射用穿琥宁与5种输液配伍的稳定性观察

Observation on stability of the kalii dehydrographolidi succinatis injection with five infusions

目的观察注射用穿琥宁与临床常用的5种药物配伍后的稳定性。方法使用各精密仪器测量观察注射用穿琥宁与5种药物在常温下配伍后0、1、2、4、8 h内外观、含量、微粒、pH值和紫外光吸收度的变化。结果注射用穿琥宁粉针剂与头孢唑林钠、地塞米松磷酸钠注射液、甲硝唑、5%葡萄糖注射液、0.9%氯化钠注射液配伍,配伍液的外观、含量、微粒、pH值和紫外光吸收度均无明显变化。结论注射用穿琥宁在临床上可与此5种药物配伍应用。

Objective To observe the stability of the kalii dehydrographolidi succinatis injection with five in-fusions in clinical. Methods The precision instruments were used to measure the injection dehydrographolidi with five drugs in the compatibility of 0,1,2,4,8 h at room temperature in appearance, content, particles, pH and UV absorbance changes. Results There was no change of compatibility fluid appearance, content,particles, pH and UV absorbance af- ter compatibility of the kalii dehydrograpbolidi succinatis with cefazolin sodium, dexamethasone sodium phosphate in- jection,metronidazole,5% glucose injection and 0. 9% sodium chloride injection. Conclusion The kalii debydrogra-pbolidi succinatis could be compatible application with the 5 drugs in clinical.