南极考察队员在不同高原环境下血氧饱和度及心率与高原反应风险的关系

Study of blood oxygen saturation, heart rate changes and plateau reaction of the Antarctic Kunlun station investigation team in different plateau environments

目的探讨南极考察队员在不同高原环境下血氧饱和度、心率变化与高原反应风险的关系。方法2010年8月至2011年4月采用无创性氧饱和度测定仪监测（MD300-C）16名南极考察队员在不同海拔情况以及不同高原环境（西藏高原和南极高原）下的血氧饱和度和心率变化以及高原反应情况，根据LakeLouiseConsensus急性高原反应症状评分和判定方法，判定急性高原反应的程度。结果16名考察队员在我国海拔110、3650、4300m时血氧饱和度、心率情况差异均有统计学意义[96．8％±1．2％、89．1％±1．2％、86．1％±2．0％，（75．0±5．4）次／min、（104．0±4．3）次／min、（113．0±5．2）次／min，F=214．155、240．088，均P〈0．05]。南极高原环境下不同海拔（2000、2500、3000、3500、4087m）血氧饱和度、心率差异也均有统计学意义[91．9％±1．3％、90．5％±1．3％、87．6％±1．4％、85．0％±1．8％、81．5％±2．2％，（85．9±3．2）次／min、（90．6±2．8）次／min、（97．8±4．1）次／min、（102．0±3．4）次／min、（106．3±3．9）次／min，F=105．418、90．174，均P〈0．05]。在南极高原环境下氧饱和度、心率与LakeLouiseConsensus急性高原病症状评分相关（r=-0．446、0．565，均P〈0．05）。结论南极考察队员在西藏高原和南极高原不同海拔下血氧饱和度、心率有明显的变化，且随着海拔的升高，高原反应风险逐渐增加。

Objective To explore the blood oxygen saturation and heart rate changes of the Antarctic expeditioners. Methods During August 2010 to April 2011, the changes in blood oxygen saturation, heart rate and plateau reaction of 16 Antarctic expedition team in different plateau environments （Tibetan plateau versus Antarctic plateau） were monitored with the noninvasive pulse oximeter MD300-C. The extent of acute mountain sickness was determined according to the Lake Louise Consensus acute mountain reaction symptom scores and judgment method. Results The changes of blood oxygen saturation, heart rate at different altitudes of 110, 3650, 4300 m （96.8% ±1.2% ,89. 1% ±1.2% ,86. 1%±2. 0% , （ 75.0 ±5.4 ） times/rain, （ 104. 0 ±4. 3 ） times/rain, （ 113.0 ±5.2 ） times/min, F = 214. 155,240. 088, both P 〈 0. 05 ）. With rising latitude and elevation gradient in Antarctic plateau, the changes of blood oxygen saturation, heart rate at different altitudes of 2000, 2500, 3000, 3500 and 4087 m （91.9% ±1.3%, 90.5% ±1.3%,87.6% ±1.4%,85.0% ±1.8%,81.5% ±2.2%,（85.9 ±3.2）times/rain,（90.6±2.8）times/rain, （97. 8 ±4. 1 ） times/rain, （102. 0 ±3.4 ） times/rain, （106. 3 ±3.9 ） times/min, F = 105.418,90. 174 ,both P 〈 0. 05 ）. Levels of blood oxygen saturation and heart rate were both correlated with the risk of altitude sickness （r = - 0. 446 and 0. 565, both P 〈 0. 05 ）. Conclusions As the increases of altitude, there are significant changes in oxygen saturation, heart rate of the Antarctic expeditioners. And with the increases of altitude, the risk of altitude sickness gradually increases.