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经鼻同步间歇正压通气辅助呼吸治疗新生儿呼吸窘迫综合征34例疗效观察 被引量:4

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摘要 目的探讨经鼻同步间歇正压通气(nasal synchronized intermittent positive pressure ventilation,NSIPPV)治疗新生儿呼吸窘迫综合征(neonatal respiratory distress syndrome,NRDS)的治疗效果。方法胎龄≤32周NRDS患儿68例,随机分为NSIPPV治疗组(观察组)和持续经鼻正压通气治疗组(对照组)各34例,分别于入院0、2、12、24、36h进行血气分析,比较氧合情况,并记录无创辅助通气时间、插管机械通气率、肺气漏等发生情况。结果 2组治疗后2h,pa(O2)及pa(CO2)均优于治疗前,但2组间比较差异无统计学意义(P>0.05);治疗后12、24及36h,观察组pa(O2)高于对照组、pa(CO2)低于对照组,2组比较差异有统计学意义(P<0.05),且同一时间点,观察组吸氧浓度及呼吸末正压均低于对照组(P<0.05);观察组无创辅助通气时间、插管机械通气率等指标优于对照组(P<0.05),无创辅助通气时间明显减少(P<0.05)。结论 NSIPPV模式治疗胎龄≤32周的NRDS更有利于肺部氧合,可缩短患儿无创通气时间、降低插管机械通气率。
出处 《中华实用诊断与治疗杂志》 2013年第7期708-710,共3页 Journal of Chinese Practical Diagnosis and Therapy
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