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重症患者是否能够应用选择性消化道去污染? 被引量:1

Uncertainties Page Should selective digestive decontamination be used in critically ill patients?
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摘要 卫生保健相关感染对重症患者是一个巨大的负担;健康保护局进行的一项最新的时点现况调查发现,23.4%的重症监护室患者有卫生保健相关感染的证据。呼吸机相关肺炎仍然是这类人群医院内感染的主要病因,虽然最近证实相关病死率(5%~10%)较以往减低,但是住院时间和治疗费用明显增加。目前认为肠道细菌的口咽部定植是呼吸机相关肺炎发展中的一个重要环节,这为口咽部去污染的干预措施提供了可能的部位。
出处 《英国医学杂志中文版》 2013年第3期185-187,共3页 The BMJ Chinese Edition
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参考文献15

  • 1Health Protection Agency. English national point prevalence survey on healtheare associated infections and antimicrobial use, 2011: preliminary data. HPA, 2012. www. hpa. org. uk/wehe! HPAwehFilel HPAweb C/1317134304594.
  • 2Melsen WG, Rovers MM, Koeman M, Bonten MJ. Estimating the attributable mortality of ventilator-associated pneumonia from randomized prevention studies. Crit Care Med 2011 ;39 :273642.
  • 3Musccdcrc JG, Martin CM, Heyland DK. The impact of ventilatorassociated pneumonia on the Canadian health care system. ] Crit Care 2008 ;23 :5-10.
  • 4Liberati A, D' Amico R, Pifferi S, Torri V, Brazzi L, Parmelli E. Antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving intensive care. Cochrane Database Syst Rev 2009; ( 4) : COO00022.
  • 5De Smet AM, Kluytmans JA, Cooper BS, Mascini EM, Benus RF, van der Werf TS. et al. Decontamination of the digestive tract and oropharynxin ICU patients. N Engl ] Med 2009 ;360 :20-31.
  • 6Bastin AJ, Hyanna KB. Use of selective decontamination of the digestive tract in United Kingdom intensive care units. Anaesthesia 2009 ;64 :46-9.
  • 7De Smet AM, Kluytmans J A. B10k HE. Mascini EM, Benus RF, Bernards AT, et al. Selective digestive tract decontamination and selective oropharyngeal decontamination and antibiotic resistance in patients in intensive-care units: an open-label, clustered group?randomised , crossover study. Lancet Infect Dis 2011 ; 11 :372-80.
  • 8De Smet AM, Hopman, TE. Minderhoud AL, Blok HE, Gossink?Franssen A, Bernards AT, et al. Decontamination of the digestive tract and oropharynx: hospital acquired infections after discharge from the intensive care unit. Intensive Care Med 2009 ;35 : 1609-13.
  • 9Oostdijk EA, de Smet AM, B10k HE, Thieme Groen ES, van Asselt GJ, Benus RF, et al. Ecological effects of selective decontamination on resistant gram-negative bacterial colonization. Am] Respir Cru Care Med 2010; 181 :452-7.
  • 10Lingnau W. Berger J, Javorsky F, Fille M, Allerberger F, Benzer H. Changing bacterial ecology during a five-year period of selective intestinal decontamination. ] Hasp Infect 1998 ;39: 195-206.

同被引文献18

  • 1Higgins J, Green S. Cochrane handbook for systematic reviews of interventions[EB/OL]. (2008 - 02)[2015 - 04]. http://www, co- chrane. Org/resources/handbook.
  • 2Aerdts SJ, van Dalen R, Clasener HA, et al. Antibiotic prophy- laxis of respiratory tract infection in mechanically ventilated patients. A prospective, blinded, randomized trial of the effect of a novel regimen [J]. Chest, 1991, 100(3) =783 - 791.
  • 3Gastinne H, Wolff M, Delatour F, et al. A controlled trial in intensive care units of selective decontamination of the diges- tive tract with nonabsorbable antibioticsEJ~. N Engl J Med, 1992, 326(9) :594- 599.
  • 4Hammond JM, Potgieter PD, Saunders GL, et al. Double- blind study of selective decontamination of the digestive tract in intensive care[J]. Lancet, 1992, 340(8810) :5 - 9.
  • 5Lingnau W, Berger J, Javorsky F, et al. Selective intestinal decontamination in multiple trauma patients: prospective, con- trolled trials[J]. J Trauma, 1997, 42(4) :687 - 694.
  • 6Quinio B, Alban6se J, Bues-Charbit M, et al. Selective decon- tamination of the digestive tract in multiple trauma patients. A prospective, double blind, randomized, placebo-controlled study[J]. Chest, 1996, 109(3) :765-772.
  • 7Rocha LA, Martin MJ, Pita S, et al. Prevention of nosocomi- al infection in critically ill patients by selective decontamination of digestive tract. A randomized, double blind, placebo-con trolled study EJ]. Intensive Care Med, 1992, 18 (7).. 398 - 404.
  • 8Stoutenbeek CP, van Saene HK, Little RA, et al. The effect of selective decontamination of the digestive tract on mortality in multiple trauma patients., a multicenter randomized con- trolled trial [J]. Intensive Care Med, 2007, 33(2) :261 - 270.
  • 9Verwaest C, Verhaegen J, Ferdinande P, et al. Randomized, controlled trial of selective digestive decontamination in 600 mechanically ventilated patients in a multidisciplinary intensive care unit ~J~. Crit Care Med, 1997, 25 (1):63-71.
  • 10Wiener J, Itokazu G, Nathan C, et al. A randomized, double- blind, placebo-controlled trial of selective digestive decontami- nation in a medical-surgical intensive care unit ~J~. Clin Infect Dis, 1995, 20 (4):861- 867.

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