不同温度的去甲肾上腺素洗胃液对洗胃中胃黏膜出血的影响

Investigate the Hemostasis Effect of Different Temperature Norepinephrine Irrigating Solution in Gastric Bleeding Caused by Gastric Lavage in Drug Poisoning

目的探讨不同温度的去甲肾上腺素洗胃液在药物中毒洗胃胃黏膜出血中的影响。方法对105例药物中毒洗胃胃黏膜出血的患者，按照入院的先后顺序随机分为恒温组53例和室温组52例。恒温组温度35-37℃，室温组温度20-22℃，两组洗胃液中去甲肾上腺素浓度均为16mg/L。结果恒温组与室温组比较各项指标比较差异有显著性（P〈0．05），室温组显效患者占86。53％，有效患者占17．31％，无变化患者0，且无1例患者出现寒战，而恒温组显效患者占49．01％，有效患者占45．28％，无变化患者占5．66％；在止血时间和所用去甲肾上腺素量方面差异显著（P〈0．05）。结论 口服药物中毒洗胃出现胃黏膜出血时采用温度20-22℃、浓度16mg／L的去甲肾上腺素洗胃液进行洗胃，止血快、去甲肾上腺素用量少，效果好。

Objective To investigate the hemostasis effect of different temperature norepinephrine irrigating solution in gaslric bleeding caused by gastric lavage in drug poisoning. Methods One hundred and five patients with gastric bleeding caused by gastric lavage in drug poisoning according to the order of admission were randomly divided into the eonstant temperature group[ n = 53） and the room tem- peratt, re（ n = 52 ）. The temperature of the constant temperature group was 35 -37℃, and the temperature of the room temperature group was 20 - 22℃. The concentration of norepinephrine irrigating solution was 16mg/L. The two groups were lavaged with irrigating solution respec- tively. Results The ,narkedly effective patients in hemostasis in the room temperature group accounted for 86.53% ,the effective 17.31% , no ineffective and ,no patients shivered. The markedly effective patients in hemostasis in the constant temperature group accounted tot 49. 01% , the effective 5.66% ,ineffective 5.66%. The room temperature group was less than the constant temperature group in hemostatic time and dosage of norepinephrine（ P 〈 0.05 ）. Conclusion Gastric lavage can stop bleeding fastly and effectively in gastric bleeding caused by gastric lavage in drng poisoning with the room temperature（20 ~ 22~C ） norepinephrine irrigating solution of whieh the dosage is less.